• Vincent Bonhomme, Pol Hans, Eric Deflandre, Stephanie Degey, Robert Poirrier, and Laurent Cambron.
• Chest. 2014 Mar 1;145(3 Suppl):586A.

Session TitleOSA PostersSESSION TYPE: Poster PresentationsPRESENTED ON: Saturday, March 22, 2014 at 01:15 PM - 02:15 PMPURPOSE: Obstructive Sleep Apnea (OSA) increases the perioperative risk. We develop a preoperative prediction score based on morphological characteristics.MethodsFollowing IRB approvals and informed consent, we included 149 patients scheduled for an overnight polysomnography (OPS). Before OPS, we measured several morphological metrics of their body, face, and neck. According to their value, each of them received a 1, 2 or 3 point(s) score. After the OPS, the AHI (Apnea Hypopnea Index: number of apnea and hypopnea per hour) was collected. Different combinations of morphological metric scores were then summed and tested for their ability to predict a severe OSA (AHI>30). This ability was calculated using ROC curve analysis and prediction probability (PK). A two-tailed P value lower than 0.05 was considered significant.Results10 patients were excluded. The best prediction score take account of four parameters: the Mallampati score, the distance between the thyroid and the chin (DTC), the body mass index (BMI) and the neck circumference (NC). According to their value, the parameters were weighted as following (1 point, 2 points, 3 points): Mallampati (Class I, Class II, Class III et IV), DTC in cm (>6, 5-6, <5), BMI in kg m-2 (>28, >39, >41), NC in cm (>37, >42, >48). The PK for an AHI>30 was 0.868 (95% CI: 0.81-0.92). The area under the curve was 0.83 (95% CI: 0.735-0.926). Sensitivity (Se) and Specificity (Sp), expressed in %, were 100 (Se) and 28.1 (Sp) for a summed score > 3, 73.1 (Se) and 78.9 (Sp) for a summed score >5, and 53.8 (Se) and 94.7 (Sp) for a summed score >6, respectively.ConclusionsOur study defines a simple morphological score for detecting OSA patients. A score > 3 presents a sensitivity of 100% and a score > 6 presents a specificity of 94.7% to identify an OSA patient with an AHI > 30.Clinical ImplicationsAnesthesiologists could use the DES-OSA score in order to detect OSA patients. The best clinical threshold is a score higher to 5 points.DisclosureThe following authors have nothing to disclose: Eric Deflandre, Vincent Bonhomme, Stephanie Degey, Laurent Cambron, Robert Poirrier, Jean-Francois Brichant, Pol HansNo Product/Research Disclosure Information.

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