• Critical care clinics · Jan 1999

    Review

    Adjuncts to analgesia. Sedation and neuromuscular blockade.

    • S M Lowson and S Sawh.
    • University of Virginia Health Sciences Center, Charlottesville, USA.
    • Crit Care Clin. 1999 Jan 1; 15 (1): 119-41, vii.

    AbstractThis article provides an overview of some of the current issues involved in sedation and anxiolysis in the intensive care unit. The problems involved in trying to monitor sedation levels are discussed, as are some of the newer options available for physiologic monitoring of the central nervous system. The problem of abnormal mental states in the intensive care unit and the range of antidepressant therapy now available are also covered. The importance of sleep deprivation and the properties of the neuromuscular blockers are also discussed.

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