• L Zhu, S Niu, and S Li.
• Institute of Respiratory Disease, Shanghai Medical University, Department of Pulmonology, Zhongshan Hospital, Shanghai 200032, China.
• Zhonghua Jie He He Hu Xi Za Zhi. 2000 Apr 1;23(4):225-7.

ObjectiveTo Evaluate the effect of nasal or oranasal face mask mechanical ventilation (FMMV) in the treatment of patients with acute respiratory distress syndrome(ARDS).Methods16 ARDS patients were separated into two groups: infection group and non-infection group. The former had 6 cases with pneumonia and 1 case with sepsis; the later had 5 cases with multiple fracture, 2 with operation of intestines obstruction, 1 with operation of spleen rupture, 1 with hepatectomy. In Infection group, the respiratory rate(RR) was (46 +/- 5) times/min, the arterial blood pH 7.49 +/- 0.05, CO2 partial pressure(PaCO2) was (32 +/- 4) mm Hg, and oxygenation index (OI) (144 +/- 23) mm Hg. In non-infection group, the RR, pH, PaCO2, OI was (41 +/- 6) times/min, 7.49 +/- 0.13, (32 +/- 5) mm Hg, (156 +/- 51) mm Hg. All patients were linked with ventilator via nasal or ornasal mask. Pressure support ventilation (PSV) and positive end-expiratory pressure (PEEP) were selected.ResultsAll patients successfully received FMMV. In infection group, RR and OI returned to (45 +/- 7) times/min (P > 0.05) and (195 +/- 30) mm Hg(P < 0.05) respectively after 2-8 hours via FMMV. But in non-infection group, the RR and OI were (35 +/- 4) times/min (P < 0.05) and (228 +/- 90) mm Hg(P < 0.05). 2 cases(29%) in infection group and 8 cases(89%) in non-infection were successfully weaned from FMMV.ConclusionFMMV could be as the first choice in ARDS patients without infection, and airway intubation should be given in infectious patients as early as possible.

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