Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
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Zhonghua Jie He He Hu Xi Za Zhi · Mar 2021
[Spatial and temporal distribution and predictive value of chest CT scoring in patients with COVID-19].
Objective: To explore a modified CT scoring system, its feasibility for disease severity evaluation and its predictive value in coronavirus disease 2019 (COVID-19) patients. Methods: This study was a multi-center retrospective cohort study. Patients confirmed with COVID-19 were recruited in three medical centers located in Beijing, Wuhan and Nanchang from January 27, 2020 to March 8, 2020. ⋯ Severe/critical patients had higher scores for ground glass opacity, consolidation, crazy-paving pattern, and overall lung involvement than moderate cases. The ground glass opacity score in the second week had an optimal predictive value for escalation of disease severity during hospitalization in moderate patients on admission. The frequency of CT scan should be reduced after entering the recovery stage.
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Zhonghua Jie He He Hu Xi Za Zhi · Dec 2020
Comparative Study[Comparison of the values of the YEARS algorithm and the simplified Wells combined with age-adjusted D-dimer algorithm in the evaluation of patients with suspected acute pulmonary embolism Wang Zhehua1, Zhou Hongbin2, Yuan Dong2, Li Gang3, Li Yaqing2. 1Zhejiang Hospital, Hangzhou 310030, China;2Department of Respiratory Medicine, Zhejiang Provincial People's Hospital (People's Hospital of Hangzhou Medical College), Hangzhou 310014, China; 3Department of Emergency Medicine, Zhejiang Provincial People's Hospital (People's Hospital of Hangzhou Medical College), Hangzhou 310014, China].
Objective: To compare the values of the YEARS algorithm and the simplified Wells combined with age-adjusted D-dimer (sWells-Age) algorithm in the evaluation of patients with suspected acute pulmonary embolism (APE). Methods: Patients with suspected APE receiving CT pulmonary angiography (CTPA) were enrolled from 2016 to 2017. With CTPA results as the gold standard, we evaluated and compared the performance of the two algorithms in the whole population and in symptom-onset site (in-hospital, out-of-hospital) subgroups. ⋯ Conclusions: The YEARS algorithm and the sWells-Age algorithm had a good diagnostic agreement and low failure rates and both could safely rule out APE. More patients with suspected APE could be safely excluded by the YEARS algorithm than the sWells-Age algorithm, especially in those suspected APE patients with out-of-hospital symptom-onset. However, both two algorithms were not applicable to suspected APE patients with in-hospital symptom-onset.
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Zhonghua Jie He He Hu Xi Za Zhi · Oct 2020
[Comparison of severity classification of Chinese protocol, pneumonia severity index and CURB-65 in risk stratification and prognostic assessment of coronavirus disease 2019].
Objective: To investigate the application of severity classification according to the protocol on the Diagnosis and Treatment of coronavirus disease 2019(COVID-19)by the National Health Commission of China, pneumonia severity index(PSI) and CURB-65 in risk stratification and prognostic assessment of COVID-19. Methods: Clinical data of 234 in-hospital patients with COVID-19 were collected and retrospectively reviewed in Wuhan Tongji Hospital. Patients were divided into 3 groups (common, severe, and critical type) at admission according to the sixth version of the protocol issued by the National Health Commission of China on Diagnosis and Treatment of COVID-19. ⋯ The optimal cut-off point of PSI was risk class Ⅳ, and the sensitivity and specificity for predicting mortality were 90.9% and 90.5%. The optimal cut-off point of CURB-65 was score 2, and the corresponding sensitivity and specificity were 84.8% and 85.6%. Conclusions: PSI and CURB-65 can be used for risk stratification and prognostic assessment in patients with COVID-19.
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Zhonghua Jie He He Hu Xi Za Zhi · Oct 2020
[Expert recommendations for the diagnosis and treatment of interstitial lung disease caused by novel coronavirus pneumonia].
COVID-19 is an acute infectious disease caused by a newly discovered coronavirus (SARS-CoV2). COVID-19 may manifest bilateral interstitial pneumonia on imaging. About 30%-60% of patients present varying degrees of interstitial changes, while most patients have a good prognosis. ⋯ Lung transplant surgery is an option for severe pulmonary fibrosis patients. Patients should receive CT following-up after be discharged from hospital, especially those whose pulmonary exudation is not well absorbed. We suggest a routine following-up on month 1, 4 and 10 after discharging, and an extended period for those who have developed irreversible interstitial fibrosis.