• J Clin Anesth · Jun 2008

    Case Reports

    Hyperosmolar, increased-anion-gap metabolic acidosis and hyperglycemia after etomidate infusion.

    • Arjunan Ganesh and Paul Audu.
    • Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, and University of Pennsylvania School of Medicine, Philadelphia, PA 19104-4399, USA. ganesha@email.chop.edu
    • J Clin Anesth. 2008 Jun 1;20(4):290-3.

    AbstractHyperosmolar increased-anion-gap metabolic acidosis without hyperglycemia has been reported after infusions of etomidate and other medications containing propylene glycol. We report a case of this biochemical abnormality with severe hyperglycemia. Cessation of the etomidate infusion along with other supportive measures resulted in prompt resolution of the metabolic acidosis and hyperglycemia.

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