• F Sztark, C Bourdallé-Badie, J L Pariente, A Lamore, P L Gardien, and P Erny.
• Département d'anesthésie-réanimation I, CHU Pellegrin, Bordeaux, France.
• Ann Fr Anesth Reanim. 1999 Apr 1;18(4):409-14.

ObjectiveEvaluation of patient-controlled sedation with propofol for extracorporeal shock wave lithotripsy (ESWL) using an EDAP LT01 lithotriptor.Study DesignProspective clinical study.PatientsFifty consecutive patients, ASA I or II, aged 18-65 years.MethodsPatients received 50 mg of propofol five minutes before ESWL, then they self-administered 50 mg bolus doses of propofol with a ten minutes lock-out interval. Pain (1-100 mm VAS) and sedation (four points scale) were assessed every five minutes. Patient satisfaction was recorded at the end of the procedure. Pharmacokinetic simulation was done with the Marsh's data set.ResultsThree patients were excluded. Patients received a mean propofol dose of 147 +/- 68 mg during the procedure with a mean duration of 47 +/- 8 minutes. The median of the higher sedation scores was 2 (drowsy) and mean maximal VAS was 40 +/- 20 mm (10-70). No complications were recorded. Thirty-nine patients (83%) were satisfied or very satisfied by patient-controlled sedation.ConclusionPatient-controlled sedation with propofol is a safe and efficient mode of administration of an hypnotic agent for ESWL.

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