• M S Angst, S C Mackey, G H Zupfer, C D Tataru, and J G Brock-Utne.
• Department of Anesthesia, Stanford University School of Medicine, CA 94305-5117, USA.
• J Clin Anesth. 1997 Sep 1;9(6):462-6.

Study ObjectiveTo investigate if the use of a new double lumen i.v. set (DLIS) decreases the incidence of propofol injection pain compared with single lumen i.v. set (SLIS) administration.DesignProspective, randomized, double-blinded study.SettingOperating rooms in a university hospital.Patients50 adult ASA physical status I and II patients of both genders undergoing general anesthesia for elective surgery.InterventionsPatients were injected with propofol either through a DLIS or a SLIS.Measurements And Main ResultsThree different pain indices were recorded to be present or absent: (1) verbal report of pain during propofol injection (2) grimacing during propofol injection, and (3) recall of injection pain in the recovery room. When the DLIS was used, the incidence of verbal pain, grimacing during propofol injection, and recall of pain during recovery were lowered significantly by 53%, 46%, and 52%, respectively (chi square analysis of contingency table with Yates correction, p < 0.05).ConclusionsThe DLIS significantly reduced the incidence of propofol injection pain compared with SLIS. Further studies are indicated to evaluate the cost-effectiveness of this device.

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