• Andrea Santamato, Francesco Panza, Serena Filoni, Maurizio Ranieri, Vincenzo Solfrizzi, Vincenza Frisardi, Annarita Dellomonaco, Maria Teresa Amoruso, Loredana Amoruso, Patrick G Kehoe, Marisa Megna, and Pietro Fiore.
• Department of Physical Medicine and Rehabilitation-'OORR Hospital', University of Foggia, Italy. a.santamato@unifg.it
• Brain Inj. 2010 Jan 1;24(9):1108-12.

BackgroundIn rehabilitation settings, motor imagery, motor observation and mirror therapy serve as techniques for the recovery of paretic upper limb in patients with movement disorders after stroke, whereas botulinum toxin type A (BTX-A) offers the best treatment for focal spasticity.Case ReportsAfter haemorrhagic stroke, three patients (two men and one woman, mean age: 61.2 +/- 7.03) presented with hemiparesis of the left or right hand and arm with flexion of fingers, wrist and elbow, with no disturbance to sensitivity but with loss of use handoff the limb to write, eat or dress. After BTX-A injections, the patients underwent a daily rehabilitation programme based on motor imagery and motor observation for 1 month. Before and after the combined treatment, the motor function, spasticity and functional deficits of the patient were extensively measured. After a 3-month follow-up, upper limb spasticity measured with the Modified Ashworth Scale had worsened, yet the associated score remained lower than that at baseline. However, in these three patients a large improvement of motor function of the hemiparetic upper limb was observed.ConclusionCombined treatment may be a viable rehabilitation option in post-stroke patients with disability to upper-extremity motor function, however further investigations are needed to determine its reproducibility in larger case series or clinical trials.

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