• Justin Pachuski, Sonia Vaida, Kathleen Donahue, John Roberts, Allen Kunselman, Benjamin Oberman, Hetal Patel, and David Goldenberg.
• Department of Anesthesiology, Head and Neck Surgery, Penn State College of Medicine and Penn State Hershey Medical Center, Hershey, PA, USA. Electronic address: jpachuski1@hmc.psu.edu.
• J Clin Anesth. 2016 Mar 1; 29: 10-3.

Study ObjectiveIntraoperative neuromonitoring of the recurrent laryngeal nerve (RLN) is often used as an adjunct for RLN identification and preservation during thyroidectomies. Laryngotracheal anesthesia (LTA) with topical lidocaine reduces coughing upon emergence from anesthesia and in the immediate postoperative period; however, its use is prohibited with concerns that it could decrease the sensitivity of the intraoperative neuromonitoring. We hypothesize that there is no difference in measurements of nerve conduction made before and after LTA administration.DesignAn observational study in which all patients were subjected to LTA administration was conducted. Recurrent laryngeal nerve threshold currents were measured before and after the intervention.SettingTertiary medical center operating room.PatientsEighteen patients (total of 25 nerves at risk) with American Society of Anesthesiologists classes 1 to 3 undergoing thyroid surgery.InterventionsAfter the thyroid was removed and threshold currents at the RLN were obtained, LTA with endotracheal lidocaine was applied on the left and right side of the in situ endotracheal tube (2 cc of 4% lidocaine per side). Threshold currents were reassessed at 5 and 10 minutes after LTA administration.MeasurementsThreshold currents (minimum stimulus current applied to the RLN required to generate a discernible electromyographic response at the vocal cords) were recorded along the RLN for a baseline at 5 and 10 mm from the insertion point of the RLN into the larynx. Threshold currents were reassessed at the same 2 positions on the RLN at 5 and 10 minutes after LTA administration. Differences in mean values, between threshold currents recorded at the 3 different times, at 2 positions on the RLN, were used to compare effects of LTA on nerve conduction.Main ResultsThere were no statistically significant differences when comparing threshold currents before and after LTA administration.ConclusionsLaryngotracheal anesthesia had no significant effect on RLN nerve conduction in the period assessed.Copyright © 2016 Elsevier Inc. All rights reserved.

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