• NeuroImage · Aug 2012

    Review Historical Article

    The future of susceptibility contrast for assessment of anatomy and function.

    • Jürgen R Reichenbach.
    • Medical Physics Group, Department of Diagnostic and Interventional Radiology I, Jena University Hospital, Friedrich-Schiller-University, Philosophenweg 3, 07743 Jena, Germany. juergen.reichenbach@med.uni-jena.de
    • Neuroimage. 2012 Aug 15;62(2):1311-5.

    AbstractThe magnetic properties of tissues affect MR images and differences in magnetic susceptibility can be utilized to provide impressive image contrast. Specifically, phase images acquired with gradient echo MRI provide unique and superb contrast which reflects variations in the underlying tissue composition. There is great interest in extracting tissue susceptibility from image data since magnetic susceptibility is an intrinsic tissue property that reflects tissue composition much more closely than MRI phase. Still, this major tissue contrast mechanism is largely unexplored in magnetic resonance imaging because non-conventional reconstruction and dipole deconvolution are required to quantitatively map tissue susceptibility properly. This short review summarizes the current state of susceptibility contrast and susceptibility mapping and aims to identify future directions.Copyright © 2012 Elsevier Inc. All rights reserved.

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