• Childs Nerv Syst · Jan 2007

    Case Reports

    Successful developmental outcome in intrauterine myelomeningocele repair.

    • Helder Zambelli, Ricardo Barini, Alexandre Iscaife, Kleber Cursino, Angélica de Fátima A Braga, Sérgio Marba, and Lourenço Sbragia.
    • Division of Pediatric Neurosurgery, Department of Neurology, State University of Campinas, UNICAMP, Campinas, Sao Paulo, Brazil.
    • Childs Nerv Syst. 2007 Jan 1;23(1):123-6.

    IntroductionMyelomeningocele (MM) is one of the forms of dysraphism. Hydrocephalus secondary to Arnold-Chiari (AC) malformation is responsible for the morbidity and mortality of the disease. The intrauterine repair of MM may reverse AC and limit hydrocephalus progression.ObjectiveThe aim of this work is to report the successful outcome of a case of intrauterine correction of MM, with favorable evolution and birth at 36 weeks of pregnancy.Case ReportKCMC, 19 years old, was submitted to intrauterine repair of MM at 24 weeks of gestational age after approval by the family and the Research Ethics Committee of the School of Medical Sciences-UNICAMP.ConclusionAlthough it is not the standard option for surgical correction, selected MM cases with early fetal diagnosis may be eligible for intrauterine repair, when there is consensus with the Research Ethics Committees and family members.

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