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Conf Proc IEEE Eng Med Biol Soc · Jan 2008
A new approach to reconstruction of central aortic blood pressure using 'adaptive' transfer function.
- Jin-Oh Hahn, H Harry Asada, Andrew T Reisner, and Farouc A Jaffer.
- Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. stardust@mit.edu
- Conf Proc IEEE Eng Med Biol Soc. 2008 Jan 1;2008:813-6.
AbstractThis paper presents a new system identification approach to the reconstruction of central aortic blood pressure signal by exploiting a non-invasive peripheral blood pressure measurement. This technique, which is called the 'adaptive' transfer function, is able to reconstruct the aortic blood pressure signal by characterizing the aortic-to-peripheral cardiovascular dynamics solely based on the peripheral measurement. In contrast to the previous related efforts, it does not require any a priori knowledge on the empirical and/or population-based relationship, e.g. the predetermined or generalized transfer function, as well as multiple peripheral measurements. The initial proof-of-principle on the efficacy of the adaptive transfer function is demonstrated by the experimental results from human and animal subjects.
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