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Rev Esp Geriatr Gerontol · Mar 2009
[Alternative to surgery in basal cell carcinoma in the elderly population: imiquimod 5% cream].
- Salvador Antonio Arias Santiago, Ricardo Ruiz Villaverde, Pilar Burkhardt Pérez, and Ramón Naranjo Sintes.
- Servicio Dermatología Hospital Clínico San Cecilio de Granada, España. salvadorarias@hotmail.es
- Rev Esp Geriatr Gerontol. 2009 Mar 1;44(2):94-7.
AbstractBasal cell carcinoma (BCC) is the most common non-melanoma skin cancer. The incidence of this entity increases with age, peaking at the age of 70 years. This study included 97 patients aged more than 65 years old, with a diagnosis of BCC. These patients were treated with imiquimod applied three times weekly for 6 weeks. Clinical remission was 67% after 10 weeks and was 49.5% after 1 year. Imiquimod is a highly interesting therapeutic modality in the elderly, in whom surgery is often contraindicated. This regimen eradicates a high percentage of tumors and reduces local adverse effects, which are poorly tolerated by aged skin.
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