• J Bronchology Interv Pulmonol · Apr 2013

    Case Reports

    Pulmonary alveolar microlithiasis and probe-based confocal laser endomicroscopy.

    • Jonas Yserbyt, Touffic Alamé, Christophe Dooms, and Vincent Ninane.
    • Department of Clinical and Experimental Medicine, Respiratory Division, University Hospitals, University of Leuven, Belgium. jonas.yserbyt@uzleuven.be
    • J Bronchology Interv Pulmonol. 2013 Apr 1;20(2):159-63.

    AbstractPulmonary alveolar microlithiasis (PAM) is a rare disease in which calcium-phosphate microliths accumulate within the alveolar space. We report cases of 2 siblings with PAM, presenting differently as regards the distribution and clinical severity. Immune cytologic analysis of bronchoalveolar lavage showed a CD4 alveolitis in the radiologically most affected patient, whereas the least affected had a normal bronchoalveolar lavage analysis, demonstrating the low specificity of immune cytologic lavage analysis in diagnosing familial PAM. For the first time, we describe the endoscopic findings using a probe-based confocal laser endomicroscopy.

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