• Arch Neurol Chicago · Dec 1984

    Pain in multiple sclerosis.

    • D B Clifford and J L Trotter.
    • Arch Neurol Chicago. 1984 Dec 1;41(12):1270-2.

    AbstractWe reviewed 317 patients with multiple sclerosis (MS) and found that the incidence of clinically significant pain, excluding headache and paresthesia, was 28.8%. Successful treatment requires recognition of the pathophysiology of the pain syndromes encountered in MS. Antidepressant drugs have been of particular value in the treatment of chronic pain in these patients.

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