• Paediatric anaesthesia · Feb 2015

    Electroencephalography for children with autistic spectrum disorder: a sedation protocol.

    • Ilan Keidan, Erez Ben-Menachem, Michal Tzadok, Bruria Ben-Zeev, and Haim Berkenstadt.
    • Department of Anesthesiology and Intensive Care, Sheba Medical Center, Tel Hashomer, Israel; Department of Anesthesiology, University of Florida, Gainesville, FL, USA.
    • Paediatr Anaesth. 2015 Feb 1;25(2):200-5.

    ObjectivesTo report the effectiveness and efficiency of a predetermined sedation protocol for providing sedation for electroencephalograph (EEG) studies in children with autism.MethodsSleep EEG has been advocated for the majority of children with autism spectrum disorder. In most cases, sedation is required to allow adequate studies. Most sedation drugs have negative effects on the EEG pattern. The sedation protocol we adopted included chloral hydrate, dexmedetomidine, and ketamine and was evaluated prospectively for 2 years.ResultsOne hundred and eighty-three children with autistic spectrum disorder were sedated with the described drug protocol that was efficient, provided adequate EEG readings, and was not associated with serious adverse events.ConclusionsOur protocol kept costs to a minimum but provided appropriate escalation in care when required.© 2014 John Wiley & Sons Ltd.

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