• Hao-lin Sun, Chun-de Li, and Shi-jun Wang.
• Department of Orthopedics, Peking University First Hospital, Beijing 100034, China.
• Beijing Da Xue Xue Bao. 2011 Oct 18;43(5):696-8.

ObjectiveTo analyze the influence of type 2 diabetes mellitus on incidence and severity of lumbar disc herniation.MethodsA total of 575 cases of lumbar disc herniation (40-70 years) from Orthopedic Department of Peking University First Hospital from October 1998 to October 2008 were retrospective studied, and the number and ratio of cases of type 2 diabetes mellitus identified. The control group included 219 cases of hallus valgus, carpal tunnel syndrome, cubital tunnel syndrome or ganglion. The number and ratio of cases of type 2 diabetes mellitus were also identified and the ratios of the two groups compared. Then we divided the lumbar disc herniation operation group into two subgroups, one with type 2 diabetes mellitus and the other without, and compared between the two subgroups the numbers of operation segments,the types of lumbar disc herniation (contained type and uncontained type) and the ratio of relapse with revision surgery by t test or χ² test.ResultsThe ratio of lumbar disc herniation group with type 2 diabetes mellitus was 15.3%(88/575) and significantly higher than 7.76%(17/219)of the control group (χ² =7.861,P=0.005), and also significantly higher than 9.94%(188/1892 ) of the incidence of type 2 diabetes mellitus in 40-70 years old people of Beijing (χ² =12.788, P=0.000 4). The operation segments were 1.19 in subgroup with type 2 diabetes mellitus and 1.15 in subgroup without type 2 diabetes mellitus(t=0.703, P=0.483);the ratios of different types of lumbar disc herniation were 65.7%(58/88)with contained type and 34.3% (30/88) with uncontained type in subgroup with type 2 diabetes mellitus as well as 70.5% (343/487) contained type and 29.5% (144/487) uncontained type in subgroup without type 2 diabetes mellitus(χ² =0.722, P=0.395); the ratios of relapse cases with revision surgery were 3.41%(3/88) in subgroup with type 2 diabetes mellitus and 3.89% (19/487) in subgroup without type 2 diabetes mellitus ( χ² =0.034,P=0.854).ConclusionPeople who received operation with lumbar disc herniation had the higher ratio concomitant with type 2 diabetes mellitus than the control group. Type 2 diabetes mellitus may increase the risk of suffering from lumbar disc herniation.

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