• Fukuoka Igaku Zasshi · Dec 1993

    [Experimental studies on the effect of heating on blood flow in the tongue of golden hamsters].

    • K Oobu.
    • First Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Kyushu University, Fukuoka.
    • Fukuoka Igaku Zasshi. 1993 Dec 1;84(12):497-511.

    AbstractThe effect of hyperthermia on the tongue of hamsters was evaluated histologically and by measuring blood flow. The dorsal tongue surface of the male mature golden hamster was heated at 41 degrees C-45 degrees C (surface temperature) by 2450 MHz microwave for 60 min, and the regional blood flow was measured using the hydrogen clearance method at 6, 24, 42, and 60 min during heating. When heated at 41 degrees C (9 animals), 42 degrees C (11 animals), 43 degrees C (8 animals), 44 degrees C (8 animals), or 45 degrees C (8 animals), the temperature of the measurement at 0.5 mm deep from the tongue surface was 38.4 +/- 1.0 degrees C, 39.3 +/- 0.6 degrees C, 40.2 +/- 0.6 degrees C, 40.8 +/- 0.5 degrees C, or 43.5 +/- 1.0 degrees C (Mean +/- S.D.), respectively. In the groups heated at 41 degrees C, 42 degrees C, 43 degrees C, 44 degrees C, the blood flow was significantly increased at the first measurement (6 min) and remained elevated during heating. The blood flow was further increased during the second heating which took place after a 2 hour interval. The group heated at 45 degrees C showed a gradual decrease in the blood flow after the initial increase. The second heating induced a slight increase to a lower blood flow than the control. Histologically, dilation and congestion of venules, hemorrhage, interstitial edema in the musculature, and swelling of muscle fibers were found. Dilation, congestion, and rapture of capillaries beneath the mucosal epithelial layer were found also. These damages were more severe with an increase in heating temperature and duration. Additionally, thromboses were found in the group heated at 45 degrees C which was examined 2 hours after heating. The heated part was necrosed in every case heated at 45 degrees C. These results suggest that the critical surface temperature at which the tongue of hamsters receive irreversible damage lies between 44 degrees C and 45 degrees C.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…