• Der Schmerz · Dec 2014

    Review Comparative Study

    [Metamizole (dipyrone): mode of action, drug-drug interactions, and risk of agranulocytosis.]

    • C Lampl and R Likar.
    • Abteilung für Neurogeriatrie und Remobilisation, Krankenhaus der Barmherzigen Schwestern Linz, Seilerstätte 4, 4020, Linz, Österreich, christian.lampl@bhs.at.
    • Schmerz. 2014 Dec 1; 28 (6): 584-90.

    AbstractMetamizole (dipyrone) is a nonsteroidal compound with strong analgesic as well as antipyretic and spasmolytic properties. Based on a small number of cases of agranulocytosis, metamizole was withdrawn from the market in some countries. Other countries restricted its use. This paper discusses the safety aspects of metamizole and compares it with other compounds used for similar indications.

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