• Joanna S M Ooi, Mohd R Abdul Rahman, Shamsul A Shah, and Mohd Z Dimon.
• Division of Cardiothoracic Anesthesia, Heart and Lung Center, Hospital University Kebangsaan Malaysia, University Kebangsaan Malaysia, Kuala Lumpur, Malaysia. joanna@mail.hukm.ukm.my
• Asian Cardiovasc Thorac Ann. 2008 Dec 1;16(6):468-72.

AbstractA prospective study was carried out to compare the outcomes of patients with preexisting non-dialysis-dependent renal dysfunction who underwent coronary artery bypass grafting with or without cardiopulmonary bypass. Elective off-pump coronary artery bypass was performed in 29 patients with renal dysfunction. Their results were compared with those of a similar group of 35 patients who underwent the conventional on-pump coronary artery grafting. There was a significant deterioration in creatinine clearance in the on-pump group on days 1, 2, and 4 after surgery, while creatinine clearance in the off-pump group remained close to the baseline level. Both groups had improved to the preoperative creatinine clearance values on follow-up at 4 weeks. It was concluded that off-pump surgery provided better renal protection than the conventional on-pump technique in patients with preexisting non-dialysis-dependent renal dysfunction.

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