• Neurol. Sci. · Sep 2002

    Case Reports

    Serotonin syndrome: a reported case.

    • T P Avarello and S Cottone.
    • Department of Neurology, Villa Sofia Hospital, Palermo, Italy.
    • Neurol. Sci. 2002 Sep 1;23 Suppl 2:S55-6.

    AbstractWe describe a patient treated with SSRI and Ldopa, who developed agitation, rigidity, hyperreflexia, restlessness, autonomic instability, fever and finally death. CSF examination, MRI of the brain, laboratory investigations, except for serum CK, glycemia and WBC, were normal. His condition was thought to result from an central serotonin activity. The serotonin syndrome occurs following the use of serotomimetic agents (serotonin reuptake inhibitors, tricyclic and tetracyclic antidepressants, tryptophan alone or in combination with monoamine oxidase inhibitors).

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