• Internal medicine · Jan 2015

    Case Reports

    Rapidly Progressive Interstitial Lung Disease Associated with Dermatomyositis Treated with Combination of Immunosuppressive Therapy, Direct Hemoperfusion with a Polymyxin B Immobilized Fiber Column and Intravenous Immunoglobulin.

    • Motohisa Takai, Naoko Katsurada, Tamao Nakashita, Masafumi Misawa, Takahiro Mochizuki, Norihiro Kaneko, Shinji Motojima, and Masahiro Aoshima.
    • Department of Pulmonary Medicine, Kameda Medical Center, Japan.
    • Intern. Med. 2015 Jan 1; 54 (17): 2225-9.

    AbstractRapidly progressive interstitial lung disease (ILD) is associated with dermatomyositis (DM) and has a high mortality rate even with immunosuppressive agents. For such cases, there is no evidence on the combined effect of direct hemoperfusion with a Polymyxin B immobilized fiber column and intravenous immunoglobulin. We herein report a case of 61-year-old woman who presented with respiratory failure. She showed ILD associated with DM which did not improve with immunosuppressive agents, but was improved with the addition of both direct hemoperfusion with a Polymyxin B immobilized fiber column and intravenous immunoglobulin.

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