• Acta Anaesthesiol Scand · May 2002

    Randomized Controlled Trial Comparative Study Clinical Trial

    The sevoflurane saving capacity of a new anaesthetic agent conserving device compared with a low flow circle system.

    • M Enlund, H Lambert, and L Wiklund.
    • University Department of Anaesthesia & Intensive Care, Uppsala, Sweden. mats.enlund@ltvastmanland.se
    • Acta Anaesthesiol Scand. 2002 May 1;46(5):506-11.

    BackgroundAn anaesthetic agent conserving device (ACD) has been added to a Bain system to approach the agent-saving capacity of a low flow circle system.MethodsRandomly selected ASA physical status I patients received a standardized anaesthetic with sevoflurane in air/O2 through either a circle system with 1.5 l/min fresh gas flow (n = 8), or through a Bain system with an added ACD with fresh gas flow 4.4-6.4 l/min (n = 8). A target controlled infusion of remifentanil was used for analgesia.ResultsThe median sevoflurane consumption was 19.7 and 22.0 ml/MAC/h with the low flow circle system and the Bain system + ACD, respectively (P=0.10, Mann-Whitney U-test), or when adjusted for weight 0.25 and 0.28 ml/MAC/h/kg (P=0.26, Mann-Whitney U-test).ConclusionThe expenditure of sevoflurane with a Bain system + ACD was close to that in a circle system with 1.5 l/min fresh gas flow. It is thereby possible to use sevoflurane to all its potential, performing for example rapid alterations in end-tidal concentration using high fresh gas flows by combining a Bain system with an ACD. Although the price is not decided for this not yet commercially available device, a potential for a lower cost exists. Additionally, there will be no concerns of toxic compounds produced in the absorber.

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