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Brain research bulletin · Aug 2003
Review Comparative StudyProtein S-100B, neuron-specific enolase (NSE), myelin basic protein (MBP) and glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and blood of neurological patients.
- K J B Lamers, P Vos, M M Verbeek, F Rosmalen, W J A van Geel, and B G M van Engelen.
- Laboratory of Pediatrics and Neurology, University Medical Centre Nijmegen, 6500 HB Nijmegen, The Netherlands. k.lamers@ckslkn.azn.nl
- Brain Res. Bull. 2003 Aug 15;61(3):261-4.
AbstractIn this study, data about protein S-100B, neuron-specific enolase, myelin basic protein and glial fibrillary acidic protein in cerebrospinal fluid and blood of patients with an acute or chronic progressive neurological disorder with brain damage are reviewed. Especially in disorders with acute brain damage, determination of these proteins in CSF and blood can be helpful to establish structural and/or functional brain damage to determine severity and prognosis of the disease process and to monitor treatment effects.
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