• J. Toxicol. Clin. Toxicol. · Jan 2000

    Case Reports

    Massive ibuprofen ingestion with survival.

    • S A Seifert, A C Bronstein, and T McGuire.
    • Rocky Mountain Poison and Drug Center, Denver, Colorado, USA. sseifert@pol.net
    • J. Toxicol. Clin. Toxicol. 2000 Jan 1;38(1):55-7.

    ObjectiveTo report a massive, 100 g ibuprofen ingestion in an adolescent, with survival.Case ReportThe patient developed coma, metabolic acidosis, and mild thrombocytopenia, but improved rapidly with supportive care. Renal function remained normal and no gastrointestinal bleeding occurred.ConclusionsMassive ingestion of ibuprofen may result in a variable picture with some elements of significant toxicity, but supportive care usually results in survival without sequelae.

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