• Funct Neurol · Jan 1989

    Age-related changes in excitability of nociceptive flexion reflex. An electrophysiological study in school-age children and young adults.

    • G Sandrini, E Alfonsi, L Ruiz, C Livieri, A P Verri, and G Nappi.
    • Department of Neurology, C. Mondino Foundation; University of Pavia, Italy.
    • Funct Neurol. 1989 Jan 1;4(1):53-8.

    AbstractBy stimulating the sural nerve at the retromalleolar level and recording EMG response from biceps femoris muscle two components can be evoked: RII (shorter latency, lower threshold, non-nociceptive) and RIII (longer latency, higher threshold, nociceptive). RIII reflex represents a useful tool for pain research in humans since a close correlation exists between the reflex threshold and that of pain. In our study, latency, amplitude, duration and threshold of RII and RIII reflexes were investigated in school-age children (aged 7-14 years) and young adults. RIII threshold was significantly lowered in children, while the other parameters were similar in both groups. Our data suggest the existence of a reduced inhibitory descending control in nociceptive spinal neurones in children.

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