• Harry J M Lemmens, David C Levi, Chuck Debattista, and John G Brock-Utne.
• Department of Anesthesia, Stanford University Medical Center, CA 94305, USA. hlemmens@leland.stanford.edu
• J Clin Anesth. 2003 Feb 1; 15 (1): 29-32.

Study ObjectiveTo determine the association between bispectral index (BIS) and seizure duration obtained by electroconvulsive therapy (ECT) administered sooner or later after anesthetic induction.DesignProspective, randomized, crossover study.SettingUniversity-affiliated medical center.PatientsNine ASA physical status I, II, and III patients undergoing a total of 31 ECTs.InterventionsECT was administered soon (<210 sec) or later (between 210 sec and 360 sec) after anesthetic induction. In each individual patient, drug regimens and ECT machine settings were identical.MeasurementsBIS immediately before the start of the ECT and the duration of the EEG seizure were recorded, as well as the time period between loss of consciousness and ECT administration.Main ResultsThere was no relationship between BIS level and seizure duration. Moreover, seizure duration was not dependent on the time of ECT administration in the time window between one and 6 minutes after loss of consciousness.ConclusionThe hypnotic drug effect measured by the BIS is not correlated to the seizure duration obtained by ECT.

20 keywords...

hide…