• J Clin Anesth · Nov 2014

    Case Reports

    Anaphylaxis to succinylated gelatin in a patient with a meat allergy: galactose-α(1, 3)-galactose (α-gal) as antigenic determinant.

    • A Uyttebroek, V Sabato, C H Bridts, L S De Clerck, and D G Ebo.
    • Faculty of Medicine, Department of Immunology, Allergology, Rheumatology, University of Antwerp, 2610 Antwerp, Belgium; Department of Immunology, Allergology, Rheumatology, Antwerp University Hospital, 2650 Antwerp, Belgium.
    • J Clin Anesth. 2014 Nov 1;26(7):574-6.

    AbstractSpecific immunoglobulin E (sIgE) antibodies towards the galactose-α(1,3)-galactose (α-gal) moieties may elicit life-threatening and fatal anaphylactic reactions. Patients sensitized to α-gal moieties from mammalian meat may also react towards mammalian gelatins and gelatin-containing drugs such as bovine gelatin-based colloid plasma substitute. The case of a 56 year old woman with a meat allergy who suffered anaphylaxis to succinylated gelatin is reported.Copyright © 2014 Elsevier Inc. All rights reserved.

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