• J Clin Anesth · Nov 2014

    Case Reports

    A patient who received clopidogrel with an indwelling epidural catheter.

    • Joshua Hamburger, Ira S Hofer, and Yury Khelemsky.
    • Department of Anesthesiology, Mount Sinai School of Medicine, 1 Gustave L. Levy Place, New York, NY 10128, USA.
    • J Clin Anesth. 2014 Nov 1;26(7):577-80.

    AbstractA patient with a drug-eluting stent placed 18 months earlier received a thoracic epidural for perioperative analgesic control as part of her thoracotomy. Postoperatively, the patient was started on clopidogrel for secondary prevention. After consultation with the Hematology service and a platelet function assay, the patient was transfused two pools of platelets and the epidural catheter was removed on postoperative day 4. The patient then underwent hourly neurologic checks for 24 hours and was discharged several days later without any negative sequelae. If neuraxial techniques and the need for clopidogrel prophylaxis come into direct conflict, vigilance is necessary for warning signs of epidural hematoma and platelet transfusion should be considered to reverse the effects of the drug.Copyright © 2014 Elsevier Inc. All rights reserved.

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