• Lenny M W van Venrooij, Rien de Vos, Mieke M M J Borgmeijer-Hoelen, Cees Haaring, and Bas A J M de Mol.
• Divisions of Dietetics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands. l.m.vanvenrooij@amc.uva.nl
• Am. J. Clin. Nutr. 2008 Jun 1; 87 (6): 1656-61.

BackgroundSeveral studies reported increased adverse outcomes after cardiac surgery in patients with low body mass index (BMI; in kg/m(2)). Little is known yet, however, about the effect of preoperative unintended weight loss (UWL) in cardiac surgery patients.ObjectiveWe explored the prevalence and effect of UWL in view of low BMI and vice versa adjusted for a validated set of preoperative risks, inflammatory activity, and duration of extracorporeal circulation on postoperative adverse outcome.DesignA prospective cohort study was performed. Nutritional data of cardiac surgery patients were collected within 24 h of admission and linked to the standard postoperative complication registration database.ResultsThe cohort consisted of 331 cases. Multivariate logistic regression analyses showed that preoperative UWL of >or=10% in the past 6 mo (>or=10%UWLin6m) was associated with a prolonged length of stay in the hospital independent from low BMI [odds ratio (OR): 7.06; 95% CI: 1.78, 28.04]. Preoperative BMI or=10%UWLin6m (OR: 4.62; 95% CI: 1.20, 17.82; and OR: 5.27; 95% CI: 1.28, 21.76, respectively). Preoperative undernutrition in cardiac surgery patients (>or=10%UWLin6m or BMI ConclusionsFrom this study, we recommend special attention for cardiac surgery patients with preoperative >or=10%UWLin6m or BMI

24 keywords...

hide…