• Neurol. Sci. · May 2006

    Review

    Medications for neuropathic pain: current trends.

    • B Colombo, P O L Annovazzi, and G Comi.
    • Department of Neurology, Headache Center, IRCCS San Raffaele Hospital, Via Olgettina 48, I-20132, Milan, Italy. colombo.bruno@hsr.it
    • Neurol. Sci. 2006 May 1; 27 Suppl 2: S183-9.

    AbstractNeuropathic pain is by definition a chronic pain condition that occurs and persists in a heterogeneous group of aetiologically different diseases characterised by a primary lesion or dysfunction of the peripheral or central nervous system. Neuropathic pain has an important prevalence in the general population, and a severe impact on quality of life and mood of affected patients. Therapy is based on tricyclic antidepressants and antiepileptic drugs, the most frequently studied drug classes. Opioids and analgesics are a second-line choice. Topical medications could be useful in several pain situations.

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