• ASDC J Dent Child · May 1997

    Randomized Controlled Trial Comparative Study Clinical Trial

    A comparative study of midazolam to meperidine/promethazine as an IM sedative technique for the pediatric dental patient.

    • A T Downs, J Dembo, G Ferretti, T D Lyons, and A Pelphery.
    • University of Kentucky College of Dentistry, USA.
    • ASDC J Dent Child. 1997 May 1; 64 (3): 197-200, 165, 228.

    AbstractThis study evaluated the efficacy and safety of midazolam (0.2 mg/kg) as an IM sedative agent in the pediatric population as compared to the standard IM meperidine (2.0 mg/kg)/promethazine (1.0 mg/kg) sedation technique. Ten pediatric dental patients, ASA Class I, were evaluated in this double-blind, randomized, crossover study. The patients ranged in age from two to four years. Vital signs, sedation levels, and anxiety levels were evaluated. Midazolam was shown to be safe, but the inferior drug compared to the standard IM meperidine/promethazine sedation technique.

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