ASDC journal of dentistry for children
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Randomized Controlled Trial Comparative Study Clinical Trial
A comparative study of midazolam to meperidine/promethazine as an IM sedative technique for the pediatric dental patient.
This study evaluated the efficacy and safety of midazolam (0.2 mg/kg) as an IM sedative agent in the pediatric population as compared to the standard IM meperidine (2.0 mg/kg)/promethazine (1.0 mg/kg) sedation technique. Ten pediatric dental patients, ASA Class I, were evaluated in this double-blind, randomized, crossover study. ⋯ Vital signs, sedation levels, and anxiety levels were evaluated. Midazolam was shown to be safe, but the inferior drug compared to the standard IM meperidine/promethazine sedation technique.