• Anesthesia and analgesia · Oct 1996

    Regional cerebral oxygen saturation during electroconvulsive therapy: monitoring by near-infrared spectrophotometry.

    • S Saito, S Miyoshi, D Yoshikawa, H Shimada, T Morita, and Y Kitani.
    • Department of Anesthesiology and Reanimatology, Gunma University School of Medicine, Maebashi, Japan.
    • Anesth. Analg. 1996 Oct 1; 83 (4): 726-30.

    AbstractElectroconvulsive therapy (ECT) increases neuronal energy consumption and alters systemic hemodynamics. We examined the effects of ECT on regional cerebral oxygen saturation (rSo2) using a near-infrared spectro-photometer. Heart rate (HR), mean arterial blood pressure (MAP), and rSo2 were continuously monitored throughout ECT under general anesthesia in 43 patients. In all subjects, rSo2 changed in a consistent pattern during ECT, initially decreasing (-9.4% +/- 0.9%) just after application of the electrical current and subsequent increasing (8.7% +/- 0.9%) beyond the pre-ECT value. A close correlation was demonstrated between the increase in rSo2 and the mean blood pressure after the electrical shock (r2 = 0.832, P < 0.0001). We conclude that ECT initially may increase cerebral metabolic rate of oxygen more than cerebral blood flow and that rapidly increasing blood pressure transiently may overwhelm cerebral pressure autoregulation.

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