• J. Neuroimmunol. · Apr 2014

    Activated microglia do not form functional gap junctions in vivo.

    • Sameh K Wasseff and Steven S Scherer.
    • Department of Neurology, The Perelman School of Medicine at the University of Pennsylvania, United States. Electronic address: swasseff@mail.med.upenn.edu.
    • J. Neuroimmunol. 2014 Apr 15; 269 (1-2): 90-3.

    AbstractWe investigated whether microglia form gap junctions with themselves, or with astrocytes, oligodendrocytes, or neurons in vivo in normal mouse brains, and in pathological conditions that induce microglial activation - brain injury and a model of Alzheimer's disease. Although microglia are in close physical proximity to glia and neurons, they do not form functional gap junctions under these pathological conditions.Copyright © 2014 Elsevier B.V. All rights reserved.

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