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Revue médicale suisse · Dec 2008
Comparative Study[Physiopathologic aspects of microcirculation in intensive care].
- N Siegenthaler, R Giraud, J-A Romand, and K Bendjelid.
- Service des soins intensifs, HUG, 1211 Genève 14.
- Rev Med Suisse. 2008 Dec 10; 4 (183): 2696-701.
AbstractIn critical care patients, microvascular alterations and perfusion heterogeneity play an important role in the persistence of cellular hypoxia despite a satisfactory functioning of the macrocirculation. Advance in the knowledge of microcirculatory pathophysiology, and its relation with the macrocirculation could be in the future a way to improve the outcome of critically ill patients. Moreover, the evolution of clinical practice towards microcirculation monitoring as a standard of care, with new therapeutic targets aimed to increase tissue perfusion, could be a revolution in critical care practice.
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