• Revue médicale suisse · Dec 2008

    Comparative Study

    [Physiopathologic aspects of microcirculation in intensive care].

    • N Siegenthaler, R Giraud, J-A Romand, and K Bendjelid.
    • Service des soins intensifs, HUG, 1211 Genève 14.
    • Rev Med Suisse. 2008 Dec 10; 4 (183): 2696-701.

    AbstractIn critical care patients, microvascular alterations and perfusion heterogeneity play an important role in the persistence of cellular hypoxia despite a satisfactory functioning of the macrocirculation. Advance in the knowledge of microcirculatory pathophysiology, and its relation with the macrocirculation could be in the future a way to improve the outcome of critically ill patients. Moreover, the evolution of clinical practice towards microcirculation monitoring as a standard of care, with new therapeutic targets aimed to increase tissue perfusion, could be a revolution in critical care practice.

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