• J Clin Anesth · Nov 1995

    Review

    Remifentanil: a new opioid.

    • P S Glass.
    • Department of Anesthesiology, Duke University, Durham, NC 27710, USA.
    • J Clin Anesth. 1995 Nov 1; 7 (7): 558-63.

    AbstractRemifentanil appears to have pharmacodynamic properties similar to other potent mu opioid agonists. It does, however, have unique pharmacokinetic properties, with a rapid onset and rapid offset of effect, irrespective of the duration of its administration. With this property, remifentanil appears to be a very titratable opioid that will make it suitable for administration for either very brief periods, in which analgesia is required, or over prolonged periods, without the concern for prolonged recovery.

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