• C S Curry, J R Darby, and B R Janssen.
• Department of Anesthesiology, Maine Medical Center, Portland, USA.
• J Clin Anesth. 1996 May 1; 8 (3): 216-9.

Study ObjectiveTo evaluate pain following laparoscopic tubal sterilization (LTS) and the effects of supplemental intraoperative fentanyl.DesignOpen evaluation of pain intensity and opioid requirements with double-blind, randomized evaluation of intraoperative fentanyl.SettingOutpatient center of a university-affiliated teaching hospital.Patients44 ASA status I patients who underwent LTS by electrocautery.InterventionsPatients received either intravenous fentanyl (F) 1 microgram/kg or saline (S) at induction.Measurements And Main ResultsPain intensity was measured with patient assessments of visual analog scales (VAS) and cumulative opioid requirements. The group that received intraoperative fentanyl received 70.2 +/- 3.7 micrograms at induction. VAS on postanesthesia care unit arrival was 4.9 +/- 0.5 (F) and 5.9 +/- 0.5 (S) (means +/- SEM). VAS after one hour was 2.1 +/- 0.2 in both groups. During that hour, the F group consumed 107.5 +/- 14.7 micrograms and the S group consumed 140.5 +/- 15.7 micrograms fentanyl. The range of fentanyl consumed by each group in the postoperative period was 0 to 250 micrograms. There were no statistically significant differences between the F and S groups.ConclusionsPain following LTS by electrocautery is of significant magnitude and may require relatively large doses of opioids for adequate management. Supplemental intraoperative fentanyl 1 microgram/kg did not produce a clinically significant reduction in either pain scores or opioid requirements.

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