• The cancer journal · Jan 2012

    Review

    Neuroimaging: diagnosis and response assessment in glioblastoma.

    • Jennifer L Clarke and Susan M Chang.
    • Department of Neurological Surgery, Division of Neuro-Oncology, University of California-San Francisco, San Francisco, CA 94143-0372, USA. clarkej@neurosurg.ucsf.edu
    • Cancer J. 2012 Jan 1; 18 (1): 26-31.

    AbstractGlioblastoma is the most common primary malignant brain tumor; standard initial treatment includes a combination of radiation and temozolomide, and treatment at recurrence often includes the use of antiangiogenic agents. Characterization of tumor at initial diagnosis, assessment of response, and ability to distinguish viable tumor from treatment effects are ongoing challenges in neuroimaging. Progress has been made with the new Response Assessment in Neuro-Oncology criteria, and new imaging modalities and combinations continue to be evaluated to further improve our ability to characterize glioblastomas at all points during their disease course.

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