• Br J Anaesth · Oct 1994

    Randomized Controlled Trial Comparative Study Clinical Trial

    Pre-emptive analgesia: comparison of preoperative with postoperative caudal block on postoperative pain in children.

    • H Holthusen, F Eichwede, M Stevens, U Willnow, and P Lipfert.
    • Department of Anaesthesiology, Heinrich-Heine-University Duesseldorf, Germany.
    • Br J Anaesth. 1994 Oct 1; 73 (4): 440-2.

    AbstractWe have compared in 25 children the effect of preoperative with postoperative caudal block on pain after circumcision in a double-blind, randomized study. After induction of anaesthesia, patients were allocated randomly to receive a caudal block either before (n = 14) or immediately after (n = 11) surgery. Postoperative pain was rated on a paediatric pain scale. If pain occurred, children received paracetamol in a dose related to body weight. Using the Mann-Whitney U test (significance < or = 0.05) there was no significant difference in cumulative postoperative analgesic requirements within the first 48 h and in times to first analgesic administration between the groups. Cumulative pain score, assessed every 30 min for the first 8 h after operation, was significantly lower for those patients who received caudal anaesthesia after operation. Thus we could not demonstrate any advantage in performing caudal block before compared with after surgery.

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