• Rev Med Inst Mex Seguro Soc · Mar 2012

    Comparative Study

    [Effect of two crystalloid fluids schemes on glucose serum levels in patients with severe preeclampsia].

    • Juan Gustavo Vázquez-Rodríguez and Alma Becerril-Serrano.
    • Unidad de Cuidados Intensivos de Adultos, Hospital de Ginecología y Obstetricia 3, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Distrito Federal, México. juangustavovazquez@hotmail.com
    • Rev Med Inst Mex Seguro Soc. 2012 Mar 1; 50 (2): 183-8.

    Backgroundtreatment of severe preeclampsia (SP) includes administration of crystalloid solutions to expand plasma circulating volume. Our objective was to compare the effects of two schemes of crystalloid solutions on glycemia in patients with SP.Methodscross-sectional study with two groups of patients: group A (123 patients) received a 10 % glucose solution and group B (146 patients) received Ringer lactate solution. We compared glycemia, endogenous creatinine clearance (ECrCl), frequency of urinary tract infection (UTI) and length of hospital stay. Student t-test and Pearson correlation coefficient were used.Resultsfinal glycemia of group A was higher than group B (168.27 ± 70.85 adversus 94.20 ± 26.63, p = 0.009). No differences were shown in ECrCl (group A 99.26 ± 30.67 adversus group B, p = 0.14) or in UTI [group A 21.95 % (27 cases) adversus group B 18.48 % (27 cases) (p = 0.43)]. Length of hospital stay was different (group A 2.2 ± 1.79 adversus group B 2.67 ± 1.78 days, p = 0.03).Conclusionspatients receiving a 10 % glucose solution presented significant hyperglycemia but not in the group receiving Ringer lactate solution.

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