• J Anaesthesiol Clin Pharmacol · Jul 2012

    Injection pain of propofol in children: A comparison of two formulations without added lidocaine.

    • Serbülent Gökhan Beyaz and Ali Eman.
    • Department of Anaesthesiology, Sakarya University Medical School, Sakarya, Republic of Turkey.
    • J Anaesthesiol Clin Pharmacol. 2012 Jul 1; 28 (3): 314-7.

    BackgroundPropofol emulsion in medium and long-chain triglycerides (MCT/LCT) has been reported to cause less injection pain than other propofol solutions in adult studies. The aim of this study was to compare the injection pain of two different propofol emulsions using two different pain scales on the pediatric population.Materials And Methods100 children scheduled for general anesthesia were divided into two groups. Patients were randomly assigned to receive propofol LCT or propofol MCT/LCT. Assessment and evaluation of the Ontario Children's Hospital Pain Scale (mCHEOPS) and the Wong-Baker Faces Scale (WBFS) were performed at the start of the injection until the patients lose consciousness.ResultsThere were no significant differences between groups in terms of demographic data. According to the mCHEOPS scale, the pain incidence of propofol LCT was 5%, whereas for propofol MCT/LCT it was 15% (P < 0.05). According to the WBFS Pain Scale, the pain incidence of propofol LCT was 17%, whereas for propofol MCT/LCT it was 21% (P > 0.05).ConclusionsPropofol MCT/LCT does not decrease injection pain; contrary to the general assumption, it causes more pain than propofol LCT in children.

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