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Randomized Controlled Trial
Effect of heated humidified ventilation on bronchial mucus transport velocity in general anaesthesia: a randomized trial.
- Hyungseok Seo, Sung-Hoon Kim, Jae-Hyung Choi, Jeong-Yeon Hong, and Jai-Hyun Hwang.
- Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
- J. Int. Med. Res. 2014 Dec 1; 42 (6): 1222-31.
ObjectiveTo evaluate the effects of heated humidified ventilation on mucociliary function during general anaesthesia.MethodsMale patients (ASA physical status 1 or 2), scheduled for elective radical retropubic prostatectomy, were allocated to receive sevoflurane general anaesthesia with conventional or heated humidified ventilation. Bronchial mucus transport velocity was assessed via fibreoptic bronchoscope and methylene blue dye at 3h after induction of anaesthesia.ResultsMedian (SE) bronchial mucus transport velocity was significantly higher in the heated humidified group (n = 26) than the conventional ventilation group (n = 24) (1.7 [0.3] mm/min vs 0.9 [0.1] mm/min).ConclusionHeated humidified ventilation effectively maintains mucociliary clearance of patients during sevoflurane general anaesthesia.© The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.
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