• Microvascular research · Jan 2009

    Review

    Alteration of microvascular permeability in acute kidney injury.

    • Timothy A Sutton.
    • Division of Nephrology, Department of Medicine, Indiana Center for Biological Microscopy, Indiana University School of Medicine, 950 West Walnut Street R-II, 202 Indianapolis, IN 46202, USA. tsutton2@iupui.edu
    • Microvasc. Res. 2009 Jan 1; 77 (1): 4-7.

    AbstractFunctional and structural abnormalities in the renal microvasculature are important processes contributing to the pathophysiology of ischemic acute kidney injury (AKI). Renewed interest in the complex interplay between tubular injury, inflammation and microvascular alterations has emerged in order to gain a better understanding of acute kidney injury syndromes. This review examines alterations of the renal microvasculature as they relate to ischemic and septic AKI with an emphasis on the mechanisms involved in altered microvascular permeability.

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