• Lung Cancer · May 2010

    Case Reports

    Combining transbronchial biopsy using endobronchial ultrasonography with a guide sheath and positron emission tomography for the diagnosis of small peripheral pulmonary lesions.

    • Hidenori Mizugaki, Naofumi Shinagawa, Kakuko Kanegae, Noriyuki Yamada, Hajime Asahina, Eiki Kikuchi, Satoshi Oizumi, Nagara Tamaki, and Masaharu Nishimura.
    • First Department of Medicine, Hokkaido University School of Medicine, North 15, West 7, Kita-ku, Sapporo 060-8638, Japan.
    • Lung Cancer. 2010 May 1; 68 (2): 211-5.

    AbstractTo evaluate the combination of transbronchial biopsy (TBB) using endobronchial ultrasonography with a guide sheath (EBUS-GS) and positron emission tomography with fluorodeoxyglucose (FDG-PET) for the diagnosis of small peripheral pulmonary lesions (PPLs) < or = 30 mm in mean diameter. A total of 74 PPLs (69.2%) were diagnosed by TBB using EBUS-GS with X-ray fluoroscopy. Diagnostic yield by FDG-PET was 78.5% for the 107 PPLs examined. Diagnostic yield with the combination of TBB using EBUS-GS and FDG-PET (90.7%) was significantly higher compared with that for each procedure alone. A significant increment in diagnostic yield with this combination was seen for PPLs >20mm and < or = 30 mm and for malignant lesions. Combination of TBB using EBUS-GS and FDG-PET is useful for the diagnosis of small PPLs.Copyright 2009 Elsevier Ireland Ltd. All rights reserved.

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