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Gen Thorac Cardiovasc Surg · Nov 2008
Review Comparative StudyLung transplantation from donation after cardiac death (non-heart-beating) donors.
- Takahiro Oto.
- Department of Cancer and Thoracic Surgery, Okayama University Hospital, 2-5-1 Shikata-cho, Okayama 700-8558, Japan. oto@md.okayama-u.ac.jp
- Gen Thorac Cardiovasc Surg. 2008 Nov 1; 56 (11): 533-8.
AbstractAlthough lung transplantation is a well-accepted treatment for advanced lung diseases, donor shortage remains a significant limiting factor resulting in an increasing number of deaths of people on waiting lists. Recently, some transplant centers have begun to use lungs retrieved from donors after circulatory arrest. This review outlines the relevant published experimental data and clinical experiences with lung transplantation from donation after cardiac-death donors (DCDs) or non-heart-beating donors (NHBDs). Techniques for lung preservation and ex vivo lung assessment of DCD (NHBD) lungs are reviewed, and aspects of primary graft dysfunction after DCD (NHBD) lung transplantation are discussed.
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