• Semin Cutan Med Surg · Jun 1999

    Review

    Keloids and hypertrophic scars: review and treatment strategies.

    • S S Urioste, K A Arndt, and J S Dover.
    • Beth Israel Deaconess Medical Center, Chestnut Hill, MA 02467, USA.
    • Semin Cutan Med Surg. 1999 Jun 1; 18 (2): 159-71.

    AbstractKeloids and hypertrophic scars represent exuberant forms of scar formation that frequently are pruritic, painful, and occasionally form strictures. As well, they may result in significant cosmetic disfigurement. Recent years have seen an increased understanding in the molecular and biological mechanisms of keloidal scar formation, allowing for the development of more specific therapeutic options for these lesions. Despite these developments, keloids and hypertrophic scars remain difficult to manage. Clinical, histopathological, and biochemical features of keloids and hypertrophic scars, as well as treatment guidelines, are discussed.

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