• B G Fahy, G M Barnas, S E Nagle, J L Flowers, M J Njoku, and M Agarwal.
• Department of Anesthesiology, University of Maryland Hospital, Baltimore, USA.
• J Clin Anesth. 1996 May 1; 8 (3): 236-44.

Study ObjectiveTo test whether the Trendelenburg ("head-down") or reverse Trendelenburg ("head-up") postures change lung and chest wall mechanical properties in a clinical condition.DesignUnblinded study, each patient serving as own control.SettingUniversity of Maryland at Baltimore Hospital, Baltimore, Maryland.Patients15 patients scheduled for laparoscopic surgery.InterventionsPatients were anesthetized and paralyzed, tracheally intubated and mechanically ventilated at 10 to 30 per minute and at a tidal volume of 250 to 800 ml. Measurements were made before surgery in supine, head-up (10 degrees from horizontal) and head-down (15 degrees from horizontal) postures.Measurements And Main ResultsAirway flow and airway and esophageal pressures were measured. From these measurements, discrete Fourier transformation was used to calculate elastances and resistances of the total respiratory system, lungs, and chest wall. Total respiratory elastance and resistance increased in the head-down posture compared with supine due to increases in lung elastance and resistance (p < 0.05); but chest wall elastance and resistance did not change (p > 0.05). Lung elastance also exhibited a negative dependence on tidal volume while head-down that was not observed in the supine posture. The change in lung elastance compared with supine was positively correlated to body mass index (weight/height2) and negatively correlated to tidal volume. Lung and chest wall elastance and resistance were not affected by shifting from supine to head-up (p > 0.05).ConclusionsThe Trendelenburg posture increases the mechanical impedance of the lung to inflation, probably due to decreases in lung volume. This effect may become clinically relevant in patients predisposed with lung disease and in obese patients.

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