• Acta Paediatr Scand · Jan 1983

    Endotoxin clearance by exchange blood transfusion in septic shock neonates.

    • H Togari, M Mikawa, T Iwanaga, N Matsumoto, A Kawase, M Hagisawa, T Ogino, R Goto, I Watanabe, H Kito, Y Ogawa, and Y Wada.
    • Acta Paediatr Scand. 1983 Jan 1; 72 (1): 87-91.

    AbstractThe role of exchange transfusion with fresh whole blood in septic shock infants was evaluated. Endotoxin was positive in 8 of 10 infants and completely removed from 6 by exchange transfusion. All 6 infants with negative endotoxins after exchange transfusions survived, but 2 with positive reactions died despite the exchange transfusion. Staphylococcus aureus was cultured in the blood from 2 infants with negative reactions and one of them survived. These findings suggested that the clearance of endotoxin has an important role in exchange transfusion among septic shock neonates.

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